Panexin BMM Serum Substitute with Defined Components, w/o: Glucocorticoide, 100 ml – P04-951SA2

Panexin BMM is a fully defined serum substitute for the cultivation of macrophages from mouse bone marrow (murine bone marrow derived macrophages, BMM) under serum- free conditions. The ready-to-use sterile solution in a final concentration of 5 % is added to the basal medium RPMI 1640, supplemented with 50 μM Mercaptoethanol and 2 ng/ml GM-CSF mur. rec.

Panexin BMM contains purified proteins, lipids, salts, amino acids, trace elements, attachment factors and hormones in an optimized formulation. It contains no growth factors, undefined hydrolysates or lysates (e. g. Peptones).

Panexin BMM has been developed for the generation of murine macrophages from bone marrow under serum- free conditions. This achieves standardized conditions and reproducible results.

Panexin BMM allows the generation of murine macrophages from bone marrow under standardized serum- free conditions. The results will be more comparable, as undefined components – like in serum-containing cultures – are eliminated. In Panexin BMM matured macrophages will show excellent attachment capabilities.